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HAIT Journal of Science and Engineering A Volume 3, Issue 1, pp. 162-168 © 2006 Holon Institute of Technology | |||||
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Clinical hyperthermia by resonant selective tumor destruction tuned by hyperfine interaction: I. Basic model
Vadim Makrin1,2 and Israel Vagner2,3,4,*
1Tel Aviv Sourasky Medical Center, 6 Weizman St., Tel Aviv 64239, Israel | 2Grenoble High Magnetic Fields Laboratory, Max-Planck-Institute für Festkörperforschung and CNRS, 25 Avenue des Martyrs, BP166, F-38042, Grenoble, Cedex 9, France 3Research Center for Quantum Communication Engineering, Holon Institute of Technology, 52 Golomb St., Holon 58102, Israel 4Cavendish Laboratory, Cambridge University, Madingley Road, Cambridge CB3 OHE, UK *Corresponding author: vagner_@hit.ac.il Received 4 December 2005, accepted 21 December 2005
| We suggest here a method for clinical hyperthermia treating by selective tumor destruction tuned by hyperfine interaction between the magnetic ions, introduced selectively in malignant cells and the nuclear spin surrounding. As a carrier for a microscopic magnetic moments the 2-deoxyglucose can be used, on which the standard by now imaging by PET (Positron Emission Tomography) is based. Influence of external frequency radiation may heat the tumor cells selectively above it basal temperature and kill the cell. Clusterization of magnetic atoms into magnetic nanoparticles within the tumor and its mechanical vibrations under external EM fields could be used to destroy the malignant cell. A new model of the hyperfine interaction between the atom spins and nuclear spins of surrounding atoms tuned by nonlinear focusing of local magnetic fields is introduced. PACS: 87.54.Br;87.66.Ur;75.30.Hx;82.60.Qr
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